The Mouse CD3 Monoclonal Antibody (AF488 Conjugated, 17A2, AGEL0663) from AssayGenie is a cutting-edge research tool specifically designed for the detection and analysis of CD3, a crucial cell surface marker involved in T cell activation and function.This high-quality antibody, conjugated with AF488 for fluorescent labeling, provides exceptional sensitivity and specificity for identifying CD3 expression in various experimental setups. Its unique monoclonal origin ensures consistent performance and accurate results across different applications, including flow cytometry, immunofluorescence, and immunohistochemistry.
By targeting CD3, a key component of the T cell receptor complex, researchers can gain valuable insights into immune responses, T cell-mediated immunity, and autoimmune diseases. This antibody's versatility and reliability make it an indispensable tool for studies in immunology, oncology, and infectious diseases, offering a deeper understanding of T cell biology and potential therapeutic targets.Elevate your research capabilities with the Mouse CD3 Monoclonal Antibody (AF488 Conjugated, 17A2, AGEL0663) from AssayGenie, and unlock new possibilities in the investigation of immune-related mechanisms and diseases.
Product Title:
GenieFluor 488 Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL0663
Size:
25µg, 100µg
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor 488 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.