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PE/Cyanine7 Anti-Mouse CD3epsilon Antibody [145-2C11] (AGEL1318)

SKU:
AGEL1318
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€159 - €399
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (PE/Cyanine7 Conjugated, 145-2C11, AGEL1318) is a powerful tool for researchers studying T cell biology and immune responses in mice. This antibody, derived from hybridoma cells, specifically targets the CD3 epsilon chain, a key component of the T cell receptor complex. The PE/Cyanine7 conjugation allows for fluorescent detection, enabling precise visualization and analysis of CD3 epsilon-expressing T cells in flow cytometry and immunofluorescence experiments. The high specificity and sensitivity of this antibody make it suitable for a wide range of applications, including cell sorting, phenotyping, and functional assays.

By targeting CD3 epsilon, this antibody provides insights into T cell activation, differentiation, and function, essential for understanding immune responses in health and disease. Whether investigating basic immunology, vaccine development, or autoimmune disorders, the Mouse CD3 Epsilon Monoclonal Antibody is a valuable tool for researchers seeking to unravel the complexities of T cell-mediated immunity in mouse models.

Product Title:PE/Cyanine7 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1318
Size:50 Tests, 100 Tests, 200 Tests
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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