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PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL1317)

SKU:
AGEL1317
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$179 - $455
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (PE/Cyanine5 Conjugated) 145-2C11 (AGEL1317) is a powerful tool for studying T cell activation and function. This antibody targets the CD3 epsilon chain, a component of the T cell receptor complex essential for T cell signaling and activation. By binding specifically to CD3 epsilon, this antibody allows for the detection and analysis of T cell populations in research settings.The 145-2C11 antibody is conjugated with PE/Cyanine5, enabling multi-color flow cytometry analysis and facilitating the identification of T cells in complex cell mixtures. Its high specificity and sensitivity make it ideal for investigating T cell responses in various experimental systems, including immunology, infectious diseases, and cancer research.

Understanding the activation and regulation of T cells is crucial for unraveling immune responses and developing targeted therapies against diseases. The Mouse CD3 Epsilon Monoclonal Antibody (PE/Cyanine5 Conjugated) 145-2C11 (AGEL1317) provides researchers with a valuable tool to advance their studies in T cell biology and immunology, contributing to the broader understanding of immune function and immune-related disorders.

Product Title:PE/Cyanine5 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL1317
Size:50 Tests, 100 Tests, 200 Tests
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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