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Biotin Anti-Mouse CD3ε Antibody [145-2C11] (AGEL0375)

SKU:
AGEL0375
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
145-2C11
Conjugation:
Biotin
Applications:
FC
€99 - €189

Description

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Biotin Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (Biotin Conjugated, 145-2C11) is a versatile tool for researchers working in the field of immunology and cell biology. This antibody, available from AssayGenie, specifically targets the CD3 epsilon chain, an essential component of the T cell receptor complex.By conjugating biotin to the antibody, researchers can easily detect and study the CD3 epsilon protein in various experimental settings. The 145-2C11 antibody is known for its high specificity and sensitivity, ensuring reliable results in applications such as flow cytometry, immunoprecipitation, and immunofluorescence.The CD3 epsilon chain is crucial for T cell activation and signaling, making this antibody invaluable for investigating T cell function, development, and responses to stimuli.

Its use can provide insights into immune responses, autoimmune disorders, infectious diseases, and cancer immunotherapy research.Whether studying basic immunology processes or exploring novel therapeutic strategies, the Mouse CD3 Epsilon Monoclonal Antibody (Biotin Conjugated, 145-2C11) offers a powerful tool to advance your research endeavors. Trust in AssayGenie's quality reagents to enhance your experiments and drive scientific discovery in the realm of immunology.

Product Title:Biotin Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL0375
Size:25µg, 100µg
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Biotin Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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