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GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11] (AGEL0377)

SKU:
AGEL0377
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
145-2C11
Conjugation:
AF 488
Applications:
FC
$191 - $479

Description

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GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11]

The Mouse CD3 Epsilon Monoclonal Antibody (AGEL0377) is a powerful tool for immunologists and researchers studying T cell biology. This antibody is conjugated with Alexa Fluor 488, allowing for easy and efficient fluorescent labeling of CD3 Epsilon, a crucial component of the T cell receptor complex. The 145-2C11 clone specificity ensures reliable and specific detection of CD3 Epsilon in mouse tissues and cell samples.CD3 Epsilon is integral for T cell activation, signaling, and function, making this antibody essential for experiments focused on understanding T cell responses in various contexts such as infection, autoimmunity, and cancer.

With its high sensitivity and specificity, the Mouse CD3 Epsilon Monoclonal Antibody (AGEL0377) is an invaluable tool for visualizing and studying T cell activation dynamics, immune responses, and T cell-mediated diseases.For researchers seeking to delve deeper into T cell biology and unravel the intricacies of immune function, this antibody provides a precise and reliable means to explore the role of CD3 Epsilon in T cell activation and function.

Product Title:GenieFluor 488 Anti-Mouse CD3ε Antibody [145-2C11]
SKU:AGEL0377
Size:50 Tests, 100 Tests, 200 Tests
Clone No:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P22646
Gene ID:12501
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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