Purified Anti-Mouse CD3ε Antibody [145-2C11] (AGEL0374)
- SKU:
- AGEL0374
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Hamster
- Isotype:
- IgG
- Clone:
- 145-2C11
- Conjugation:
- Unconjugated
- Applications:
- FC
- WB
- IHC
- IF
- IP
Frequently bought together:
Description
Product Title: | Purified Anti-Mouse CD3ε Antibody [145-2C11] |
SKU: | AGEL0374 |
Size: | 25µg, 100µg |
Clone No: | 145-2C11 |
Synonyms: | T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E; |
Host Species: | Armenian Hamster |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Armenian Hamster IgG |
Isotype Control: | Purified Armenian Hamster IgG Isotype Control[PIP] |
Form: | Liquid |
Conjugation: | Unconjugated |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P22646 |
Gene ID: | 12501 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |