null

Mouse CD3/CD28 T Cell Activation Beads (AKES213)

SKU:
AKES213
Size:
1 mL
Host Species:
Hamster
Reactivity:
Mouse
  • Mouse CD3/CD28 T Cell Activation Beads (AKES213)
  • Mouse CD3/CD28 T Cell Activation Beads (AKES213)
€639

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name: Mouse CD3/CD28 T Cell Activation Beads
SKU: AKES213
Size: 1 mL
Host Species: Hamster
Reactivity: Mouse
Feature: Activation and expansion of sorted T cells or T cells from mouse spleen
Form: Liquid
Isolation Technology: Magnetic Beads
Sample Type: Spleen, Lymph nodes, Whole blood, Pre-isolated T-cells
Clonality: Monoclonal
Cell Type: T cells
Formulation: Consists of 1×108 beads dissolved in phosphate buffered saline (PBS)
Usage: Add 10 µL of beads per 1×106 T cells
Storage: This product can be stored at 2-8°C for 12 months, do not freeze.
Description: Two types of signals are required to induce T cell activation and proliferation: one is a specific antigen-stimulating signal generated by the binding of TCR/CD3 complex to the specific MHC II antigen-peptide complex on the surface of antigen-presenting cells (APCs); the other is a non-specific co-stimulatory signal generated by the interaction of co-stimulatory molecules on the surface of APCs with the corresponding receptors on the T cells, of which CD28 is one of the co-stimulatory molecule. The Mouse CD3/CD28 T Cell Activation Beads is used for activation and expansion of sorted mouse T cells or T cells from mouse spleen.
Intend Use: Mouse CD3/CD28 T Cell Activation Beads are made by coupling anti-CD3 and anti-CD28 antibodies to magnetic beads, which can provide the primary TCR signal and co-stimulatory signals required for T-cell activation and expansion, thus inducing T-cell activation and proliferation in vitro. For subsequent relevant experimental studies, this beads can be removed from cultured cells by using a magnetic rack.

Related Products