The Mouse CD28 Monoclonal Antibody (APC Conjugated) (37-51) is a specialized research tool offered by Assay Genie for immunological studies. This antibody is specifically designed to target the CD28 protein, a crucial co-stimulatory molecule involved in T-cell activation and immune response regulation.The APC-conjugated monoclonal antibody is optimized for flow cytometry applications, allowing for accurate and reliable detection of CD28 expression on various cell types. By binding to CD28, researchers can analyze T-cell activation, proliferation, and differentiation processes, providing valuable insights into immune function.
With its high specificity and sensitivity, the Mouse CD28 Monoclonal Antibody (APC Conjugated) (37-51) is an essential tool for investigating immune responses in both basic research and clinical settings. Researchers studying immunology, infectious diseases, autoimmunity, and cancer immunotherapy will find this antibody invaluable for their experiments and discoveries.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P31041
Gene ID:
12487
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.