The Mouse CD28 Monoclonal Antibody (AF647 Conjugated, 37-51) from AssayGenie (AGEL0765) is a cutting-edge tool for researchers studying the CD28 molecule, a key regulator of T cell activation and immune response. This monoclonal antibody, conjugated with AF647 for enhanced detection, offers high specificity and sensitivity in various applications.CD28 is a critical co-stimulatory receptor expressed on T cells that provides essential signals for T cell activation, proliferation, and cytokine production. By targeting CD28 with this specific antibody, researchers can investigate its role in immune signaling pathways, T cell function, and immune-related diseases.
The AF647 conjugation enables easy and efficient visualization of CD28 expression in flow cytometry, immunofluorescence, and other experimental techniques.This Mouse CD28 Monoclonal Antibody is rigorously validated for use in research involving mouse samples, offering reliable results and consistent performance. Its ability to selectively bind to CD28 makes it a valuable tool for immunologists, cancer biologists, and researchers studying immune-related disorders. Gain deeper insights into T cell biology and immunotherapy with the precision and reliability of the Mouse CD28 Monoclonal Antibody (AF647 Conjugated, 37-51) from AssayGenie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P31041
Gene ID:
12487
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.