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Purified Anti-Mouse CD28 Antibody [37.51] (AGEL0135)

SKU:
AGEL0135
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
37.51
Conjugation:
Unconjugated
Applications:
FC
IHC
IP
$131 - $239
Frequently bought together:

Description

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Purified Anti-Mouse CD28 Antibody [37.51]

The CD28 Monoclonal Antibody (AGEL0135) offered by AssayGenie is a cutting-edge tool designed for research involving CD28, a crucial cell surface receptor involved in T cell activation and immune response regulation. This monoclonal antibody is specifically engineered for high reactivity with mouse samples, providing reliable and consistent results in various applications.CD28 is a co-stimulatory molecule essential for optimal T cell activation and proliferation, making it a key player in adaptive immune responses. The ability of this monoclonal antibody to bind to CD28 with high specificity enables accurate detection and analysis of CD28 expression in different cell types, making it an invaluable asset for immunology research.

Moreover, CD28 has been identified as a promising target for therapeutic interventions in diseases such as cancer, autoimmune disorders, and infectious diseases. Research involving CD28 modulation has the potential to unlock novel treatment strategies by manipulating T cell responses and enhancing immune surveillance against pathogens and tumors. The precise and reliable performance of the CD28 Monoclonal Antibody (AGEL0135) makes it an indispensable tool for advancing our understanding of CD28 biology and its implications in various disease settings.

Product Title:Purified Anti-Mouse CD28 Antibody [37.51]
SKU:AGEL0135
Size:25µg, 100µg
Clone No:37.51
Synonyms:T-cell-specific surface glycoprotein CD28;Cd28;CD28;
Host Species:Syrian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P31041
Gene ID:12487
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.

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