The Mouse CD25 Monoclonal Antibody (PE/Cyanine7 Conjugated) PC-61.5.3 (AGEL1300) is a cutting-edge immunological tool designed for precise research applications involving CD25, a crucial cell surface marker associated with regulatory T cells. This monoclonal antibody, conjugated with PE/Cyanine7, offers exceptional sensitivity and specificity when analyzing CD25 expression in mouse samples.CD25, also known as interleukin-2 receptor alpha chain, plays a pivotal role in immune regulation by promoting the development and function of regulatory T cells that maintain immune tolerance and prevent autoimmune responses. Its function in modulating immune responses makes CD25 a key target for investigations in immunology, autoimmunity, and cancer research.
The PC-61.5.3 monoclonal antibody enables precise detection of CD25 expression, allowing researchers to delve deep into understanding the role of regulatory T cells in various physiological and pathological conditions.By utilizing the Mouse CD25 Monoclonal Antibody (PE/Cyanine7 Conjugated) PC-61.5.3 (AGEL1300), researchers can uncover valuable insights into immune modulation, tolerance mechanisms, and the intricate interplay between regulatory T cells and other immune cell populations. This antibody is a powerful asset for studies aiming to unravel the complexities of immune regulation and develop innovative therapies for immune-related disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01590
Gene ID:
16184
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.