The Mouse CD25 Monoclonal Antibody (AF488 Conjugated, PC 61.5.3) is a powerful tool for research purposes, particularly in the field of immunology. This antibody, available from Assaygenie, targets the CD25 molecule, also known as the interleukin-2 receptor alpha chain. The conjugation with AF488 allows for easy detection and visualization in various assays.CD25 is a crucial cell surface receptor involved in regulating the immune response, specifically in T cell activation and proliferation. By targeting CD25, researchers can gain insights into T cell function, immune tolerance, and immune system dysregulation in diseases like autoimmune disorders, allergies, and cancer.
This monoclonal antibody, recognized as PC 61.5.3, offers high specificity and sensitivity in detecting CD25 in mouse samples. Its validation for use in various immunological assays, such as flow cytometry and immunofluorescence, makes it an essential tool for investigating immune responses and developing targeted therapies.Overall, the Mouse CD25 Monoclonal Antibody (AF488 Conjugated, PC 61.5.3) from Assaygenie is a valuable resource for researchers aiming to explore the intricacies of immune regulation and T cell biology in preclinical and experimental settings.
Genie Fluor 488 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01590
Gene ID:
16184
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.