The Mouse CD24 Monoclonal Antibody (PE/Cyanine7 Conjugated) M1/69 (AGEL1895) is an essential tool for researchers studying CD24, a glycosylphosphatidylinositol-anchored cell surface protein with diverse roles in immune regulation, cell adhesion, and signaling pathways. This antibody, specifically conjugated with PE/Cyanine7, offers high sensitivity and specificity in flow cytometry and immunofluorescence applications.CD24 is known for its involvement in cell differentiation, proliferation, and migration, making it a key molecule in developmental biology and cancer research. The Mouse CD24 Monoclonal Antibody M1/69 (AGEL1895) recognizes the CD24 protein with high affinity, enabling precise detection and analysis in mouse samples.
Its use is validated for various experimental settings, including in vitro and in vivo studies, providing valuable insights into the role of CD24 in immune responses and disease progression.With CD24 being implicated in immune cell interactions and tumor progression, this antibody is a valuable tool for investigating the mechanisms underlying immune responses, tumor immunology, and potential therapeutic targets. By targeting CD24, researchers can uncover novel insights into cancer biology, immunotherapy, and autoimmune disorders, advancing our understanding of disease pathways and facilitating the development of innovative treatments.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24807
Gene ID:
12484
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD24 is a 35-45 kD protein also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, and dendritic cells. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.