The Mouse CD210 Monoclonal Antibody (Biotin Conjugated, 1B1/3A) is a specialized tool for researchers studying CD210, a cell surface receptor involved in immune signaling pathways and inflammatory responses. This antibody, produced through monoclonal techniques, exhibits high specificity for mouse samples and is optimized for various experimental applications, including immunohistochemistry and flow cytometry.CD210, also known as a key regulator of immune responses, plays a pivotal role in modulating the activation of immune cells and regulating cytokine production.
Its involvement in inflammatory processes makes it a target of interest for investigating immune-related disorders, such as autoimmune diseases and infectious conditions. By targeting CD210 with this monoclonal antibody, researchers can gain insights into the function and expression of this receptor in different cellular contexts, contributing to advancements in immunology and therapeutic development.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
Q61727
Gene ID:
16154
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.