The Mouse CD210 Monoclonal Antibody (1B1-3A, AGEL0163) is a premium-grade antibody developed for research applications targeting CD210, a cell surface receptor known to be involved in immune responses and inflammation modulation. This monoclonal antibody, created specifically for mouse samples, is meticulously validated for a range of experimental techniques, including immunohistochemistry, flow cytometry, and ELISA.CD210, also referred to as the marker for a cell population implicated in immune regulation, plays a pivotal role in modulating inflammatory processes and orchestrating immune responses. Researchers in immunology and related fields can leverage the unique reactivity and specificity of this antibody to explore the functions and mechanisms underlying CD210, shedding light on its implications in various physiological and pathological conditions.
With its ability to precisely target and detect CD210 in diverse cell types and experimental setups, the Mouse CD210 Monoclonal Antibody (1B1-3A, AGEL0163) stands as a valuable tool for investigations into immune system behavior, autoimmune diseases, infectious disorders, and other areas where immune regulation is a focal point of study. Explore the intricate landscape of CD210 biology with this reliable and cutting-edge research reagent.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.