The Mouse CD209B Monoclonal Antibody (Biotin Conjugated, 22D1 - AGEL0126) available at Assaygenie is a valuable tool for researchers studying CD209B, a cell surface protein involved in immune responses. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, is specifically designed for detecting and analyzing CD209B expression in various experimental settings.CD209B, also known as dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) homolog, is a key player in immune recognition and response modulation. Its role in pathogen recognition and antigen presentation makes it a significant target for research in immunology, infectious diseases, and vaccine development.
The Mouse CD209B Monoclonal Antibody provided by Assaygenie enables precise detection and analysis of CD209B expression, facilitating in-depth exploration of its functions in different cell types and experimental conditions.With its high specificity and sensitivity, this antibody is ideal for various applications, including immunofluorescence, flow cytometry, and immunohistochemistry. By using the Mouse CD209B Monoclonal Antibody (Biotin Conjugated, 22D1 - AGEL0126), researchers can gain valuable insights into the mechanisms underlying immune responses and potentially contribute to the development of new therapeutic strategies targeting CD209B-mediated pathways.
Product Title:
Biotin Anti-Mouse CD209b Antibody [22D1]
SKU:
AGEL0126
Size:
25µg, 100µg
Clone No:
22D1
Synonyms:
CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7;CD209;Cd209b;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
Biotin Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
Q8CJ91
Gene ID:
69165
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.