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Biotin Anti-Mouse CD1d Antibody [19G11] (AGEL0148)

SKU:
AGEL0148
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
19G11
Conjugation:
Biotin
Applications:
FC
€99 - €179
Frequently bought together:

Description

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Biotin Anti-Mouse CD1d Antibody [19G11]

The Mouse CD1d Monoclonal Antibody (Biotin Conjugated, 19G11, AGEL0148) from Assay Genie is a premium research tool designed for scientists studying CD1d, a cell surface molecule crucial for immune system function, particularly in the context of antigen presentation to natural killer T (NKT) cells. This monoclonal antibody, derived from hybridoma clone 19G11 and conjugated with biotin for increased versatility in detection assays, exhibits high specificity and sensitivity in recognizing mouse CD1d protein.CD1d plays a pivotal role in the immune system by presenting lipid antigens to NKT cells, thereby initiating immune responses and regulating tolerance. This antibody has been rigorously validated for various applications, including flow cytometry, immunoprecipitation, and immunohistochemistry, offering researchers a reliable tool for investigating CD1d expression and function in mouse models.

With its ability to specifically target CD1d, this antibody facilitates the detection and analysis of CD1d expression in different cell types, making it an essential asset for studies focusing on immunology, autoimmunity, infectious diseases, and cancer immunotherapy. By deepening our understanding of CD1d-mediated immune responses, researchers can unlock new insights and therapeutic strategies for combating various diseases and disorders.

Product Title:Biotin Anti-Mouse CD1d Antibody [19G11]
SKU:AGEL0148
Size:25µg, 100µg
Clone No:19G11
Synonyms:Antigen-presenting glycoprotein CD1d1;Cd1d1;CD1d.1;Cd1d1;Cd1.1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P11609
Gene ID:12479
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.

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