The Mouse CD19 Monoclonal Antibody (PE/Cyanine7 Conjugated) is a powerful tool for research involving CD19, a cell surface protein crucial for B cell development and function. This highly specific monoclonal antibody, designated as 1D3 (AGEL0474), is conjugated with PE/Cyanine7 for fluorescence detection and analysis in flow cytometry and immunofluorescence applications.CD19 is a key biomarker for B cell identification and activation, playing a vital role in adaptive immune responses. The 1D3 monoclonal antibody recognizes CD19 with high affinity, enabling precise detection and characterization of B cells in various experimental settings. Its conjugation with PE and Cyanine7 allows for multiparameter analysis and visualization of CD19-positive cells in complex cell populations.
This monoclonal antibody is essential for immunology research, particularly in studies focusing on B cell biology, immunotherapy, and immunophenotyping. Its reliable performance and specificity make it an indispensable tool for investigating B cell-related disorders, autoimmune diseases, and immune response modulation. Researchers can confidently rely on the Mouse CD19 Monoclonal Antibody (PE/Cyanine7 Conjugated) 1D3 (AGEL0474) to advance their understanding of B cell dynamics and immune system functionality.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.