The Mouse CD19 Monoclonal Antibody (FITC-Conjugated 1D3, AGEL0469) available on www.assaygenie.com is a valuable tool for research involving the CD19 cell surface molecule. CD19 is a well-known B-cell marker and plays a crucial role in B-cell development, activation, and differentiation. This monoclonal antibody is specifically designed to bind to the CD19 protein, allowing for its detection and analysis in various experimental settings.The FITC conjugation of this antibody provides the advantage of fluorescent labeling, enabling visualization and quantification of CD19-expressing cells through flow cytometry and immunofluorescence techniques. This feature makes the antibody particularly useful for studies focusing on B-cell biology, immunology, and antibody-based therapies.
Additionally, the high specificity and reactivity of the 1D3 clone ensure reliable and consistent results in research applications.Furthermore, this Mouse CD19 Monoclonal Antibody holds promise for investigating B-cell-related disorders, such as leukemia, lymphoma, and autoimmune diseases, by facilitating the identification and characterization of CD19-positive cell populations. Its reliability and performance make it an essential reagent for scientists and researchers studying B-cell biology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.