The Mouse CD19 Monoclonal Antibody (APC-conjugated, 1D3) is a powerful tool for research involving CD19, a key cell surface marker found primarily on B cells. This antibody, derived from mouse hybridoma cells, demonstrates high specificity and sensitivity in detecting CD19 expression in various experimental setups such as flow cytometry and immunofluorescence.CD19 is a critical component of B cell development, activation, and differentiation, making it an essential target in immunology research, particularly in studying B cell-related disorders like leukemia and lymphoma. The APC-conjugated 1D3 antibody binds specifically to CD19, enabling precise identification and analysis of B cells in complex biological samples.
With its reliable performance and ability to facilitate accurate quantification of CD19-expressing cells, the Mouse CD19 Monoclonal Antibody (APC-conjugated, 1D3) is an invaluable tool for investigators in immunology, oncology, and other fields where B cell biology is a focus of study. Whether used for basic research or clinical applications, this antibody provides a robust platform for exploring the role of CD19 and B cells in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.