Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL0428)
- SKU:
- AGEL0428
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Hamster
- Isotype:
- IgG
- Clone:
- CXCR3-173
- Conjugation:
- Unconjugated
- Applications:
- FC
Frequently bought together:
Description
Product Title: | Purified Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] |
SKU: | AGEL0428 |
Size: | 25µg, 100µg |
Clone No: | CXCR3-173 |
Synonyms: | C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3; |
Host Species: | Armenian Hamster |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Armenian Hamster IgG |
Isotype Control: | Purified Armenian Hamster IgG Isotype Control[PIP] |
Form: | Liquid |
Conjugation: | Unconjugated |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | O88410 |
Gene ID: | 12766 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |