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Biotin Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL0429)

SKU:
AGEL0429
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
CXCR3-173
Conjugation:
Biotin
Applications:
FC
$179 - $263
Frequently bought together:

Description

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Biotin Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The CXCR3 Monoclonal Antibody (AGEL0429) is a biotin-conjugated antibody specifically designed for researchers studying the CXCR3 protein in mouse models. The antibody, generated using cutting-edge technology, is highly sensitive and specific, allowing for accurate detection and analysis of CXCR3 expression in various tissues and cell types.CXCR3 is a chemokine receptor involved in immune responses, inflammation, and cell migration. It plays a critical role in immune cell trafficking and activation, making it a key target for studies in immunology, inflammation, and autoimmune diseases. The CXCR3 Monoclonal Antibody enables researchers to explore the function and regulation of CXCR3, shedding light on its role in disease pathology and potentially leading to the development of targeted therapies.

This biotin-conjugated antibody is optimized for applications such as immunohistochemistry, flow cytometry, and immunofluorescence, providing researchers with versatile tools to investigate CXCR3 biology in depth. By utilizing the CXCR3 Monoclonal Antibody, researchers can advance their understanding of immune response mechanisms and potentially uncover new therapeutic targets for a range of diseases.

Product Title:Biotin Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL0429
Size:25µg, 100µg
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Biotin Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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