PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1425)
- SKU:
- AGEL1425
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Applications:
- FC
Frequently bought together:
Description
Product Title: | PE/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] |
SKU: | AGEL1425 |
Size: | 50 Tests, 100 Tests, 200 Tests |
Clone No: | CXCR3-173 |
Synonyms: | C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3; |
Host Species: | Armenian Hamster |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Armenian Hamster IgG |
Isotype Control: | PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP] |
Form: | Liquid |
Conjugation: | PE/Cyanine 5.5 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Spectrum: |
Swissprot: | O88410 |
Gene ID: | 12766 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |