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FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1422)

SKU:
AGEL1422
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€169 - €389
Frequently bought together:

Description

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FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The Mouse CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (CXCR3-173) is a cutting-edge tool designed for researchers studying the CXCR3 protein in mouse samples. This monoclonal antibody, conjugated with FITC for fluorescent detection, specifically targets CXCR3, a chemokine receptor involved in immune responses and inflammation regulation.CXCR3 is a key player in directing immune cell migration and activation in various physiological and pathological conditions. Its role in modulating inflammatory responses makes it a target of interest in research areas such as immunology, cancer biology, and infectious diseases.

The CXCR3-173 antibody is rigorously tested and validated for use in flow cytometry and immunofluorescence applications, allowing precise detection and analysis of CXCR3 expression in different cell types and tissues.By utilizing the Mouse CD183 (CXCR3) Monoclonal Antibody FITC Conjugated (CXCR3-173), researchers can gain insights into the function and regulation of CXCR3, paving the way for a deeper understanding of immune responses and the development of novel therapeutic strategies targeting this crucial chemokine receptor.

Product Title:FITC Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1422
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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