GenieFluor 488 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0492)
- SKU:
- AGEL0492
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FC
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- IgG2a,k
- Clone:
- PK136
- Conjugation:
- AF 488
Frequently bought together:
Description
Product Title: | GenieFluor 488 Anti-Mouse CD161/NK1.1 Antibody [PK136] |
SKU: | AGEL0492 |
Size: | 25µg, 100µg |
Clone No: | PK136 |
Synonyms: | Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c; |
Host Species: | Mouse |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Mouse IgG2a, κ |
Isotype Control: | Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4] |
Form: | Liquid |
Conjugation: | Genie Fluor488 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
Spectrum: |
Swissprot: | P27814 P27812 Q99JB4 |
Gene ID: | 17059 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |