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Purified Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0050)

SKU:
AGEL0050
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
2.4G2
Conjugation:
Unconjugated
Applications:
FC
$95 - $167
Frequently bought together:

Description

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Purified Anti-Mouse CD16/32 Antibody [2.4G2]

The Mouse CD16/32 Monoclonal Antibody (2.4G2) is designed for research involving CD16/32, critical cell surface molecules known for their roles in immune response regulation, specifically in the processes of antibody-dependent cellular cytotoxicity and phagocytosis. This monoclonal antibody, produced in mice, is highly reactive with mouse samples and is validated for use in flow cytometry applications. It binds to CD16/32 proteins, enabling precise detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.CD16 (FcγRIII) and CD32 (FcγRII) are receptors for the Fc region of immunoglobulins and play pivotal roles in immune complex-mediated responses, including inflammation and immune cell activation.

The Mouse CD16/32 Monoclonal Antibody (2.4G2) is a valuable tool for researchers studying mechanisms of immune response, autoimmune disorders, and cancer immunotherapy. Its ability to block Fc receptor binding sites also makes it indispensable in experiments requiring Fc receptor blockade to prevent non-specific binding.Understanding the activity of CD16 and CD32 is crucial for the development of targeted therapies that manipulate immune function. By providing accurate detection and reliable analysis of CD16/32, this antibody supports comprehensive studies of immune regulation pathways. The Mouse CD16/32 Monoclonal Antibody (2.4G2) is essential for advancing research in immunology, autoimmune diseases, and cancer therapy development.

Product Title:Purified Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:AGEL0050
Size:25µg, 100µg
Clone No:2.4G2
Synonyms:CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:Rat
Reactivity:Mouse
Application:FCM;Block
Isotype:Rat IgG2b, κ
Isotype Control:Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P08508 P08101
Gene ID:14130,14131
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

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