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PE Anti-Mouse CD150 Antibody [TC15-12F12.2] (AGEL1883)

SKU:
AGEL1883
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$203 - $551
Frequently bought together:

Description

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PE Anti-Mouse CD150 Antibody [TC15-12F12.2]

The Mouse CD150 Monoclonal Antibody (PE Conjugated, TC15-12F12.2, AGEL1883) offered by Assay Genie is a specialized tool for researchers working with CD150, a cell surface marker involved in immune cell function and hematopoiesis. This antibody, derived from mouse monoclonal sources, is optimized for flow cytometry applications, allowing precise detection and analysis of CD150 expression in mouse samples.CD150, also known as signaling lymphocytic activation molecule family member 1 (SLAMF1), is a key regulator of immune cell activation and differentiation. Its expression is found on various immune cell subsets, including T and B cells, and is essential for proper immune responses and hematopoietic cell development.

The Mouse CD150 Monoclonal Antibody enables researchers to investigate the role of CD150 in immune cell interactions, immune system development, and hematopoiesis.Utilizing this antibody opens up opportunities for in-depth studies in immunology, hematopoiesis, and related fields. By understanding the functions and regulatory mechanisms of CD150, researchers can gain insights into immune cell behavior, immune system disorders, and potential therapeutic interventions targeting CD150 pathways. The Mouse CD150 Monoclonal Antibody is a valuable tool for advancing research in immunology, hematology, and beyond.

Product Title:PE Anti-Mouse CD150 Antibody [TC15-12F12.2]
SKU:AGEL1883
Size:25µg, 100µg
Clone No:TC15-12F12.2
Synonyms:Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, λ
Isotype Control:PE Rat IgG2a, λ Isotype Control[B39-4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QUM4
Gene ID:27218
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

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