The Mouse CD14 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (SA14-2) is a cutting-edge research tool designed for investigating the role of CD14, a key cell surface receptor involved in the innate immune response. This monoclonal antibody, labeled with PERCP-Cyanine5.5, specifically targets mouse CD14, offering high specificity and sensitivity in experimental applications.CD14 is a crucial component of the innate immune system, serving as a pattern recognition receptor that plays a pivotal role in the detection of bacterial lipopolysaccharide (LPS) and other microbial components. By binding to CD14, this antibody enables precise detection and analysis of mouse CD14 expression in various cell types, making it a valuable asset for studies in immunology, infectious diseases, and inflammatory processes.
Researchers can utilize the Mouse CD14 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (SA14-2) to unravel the mechanisms underlying immune responses, including inflammation, pathogen recognition, and immune cell activation. Its application extends to flow cytometry, immunofluorescence, and other analytical techniques, providing comprehensive insights into the functions of CD14 in physiological and pathological conditions.For scientists seeking to delve deeper into the innate immune system and its regulatory pathways, the Mouse CD14 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (SA14-2) stands as a reliable and effective tool, facilitating advanced research endeavors with precision and accuracy.
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.