The Mouse CD14 Monoclonal Antibody (PE-Cyanine5.5 Conjugated, SA14-2, AGEL1868) is a specialized tool for researchers studying mouse CD14, a key cell surface receptor involved in immune response regulation and pathogen recognition. This monoclonal antibody, conjugated with PE-Cyanine5.5, provides a reliable method for detecting and analyzing CD14 expression in mouse samples using flow cytometry or other fluorescence-based techniques.CD14 is a crucial component of the innate immune system, playing a central role in the recognition of bacterial lipopolysaccharide (LPS) and other microbial components. By binding specifically to CD14, the SA14-2 antibody allows for precise identification and characterization of mouse cells expressing this important receptor.
This capability is particularly valuable for researchers investigating immune cell activation, inflammatory responses, and infectious diseases in mouse models.With its high specificity and sensitivity, the Mouse CD14 Monoclonal Antibody (PE-Cyanine5.5 Conjugated, SA14-2, AGEL1868) offers a powerful tool for advancing immunological research and understanding the intricate mechanisms underlying immune responses in mice. Researchers can utilize this antibody to explore the functions of CD14 in various cellular contexts, paving the way for new insights into immune system regulation and potential therapeutic targets for immune-related disorders.
Product Title:
PE/Cyanine5.5 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1868
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.