The Mouse CD14 Monoclonal Antibody (AF647 Conjugated) SA14-2 (AGEL1871) is an essential tool for researchers studying the CD14 protein, a key component of the innate immune system. This monoclonal antibody, conjugated with AF647 for fluorescence detection, is specifically designed for use in flow cytometry and fluorescence microscopy applications.CD14 is a crucial biomarker for immune cells, particularly macrophages and monocytes, playing a pivotal role in the recognition of bacterial lipopolysaccharides (LPS) and subsequent activation of immune responses. By utilizing the Mouse CD14 Monoclonal Antibody (AF647 Conjugated) SA14-2 (AGEL1871), researchers can accurately detect and quantify the expression of CD14 in various cell populations, providing insights into immune cell function and response to pathogens.
This antibody offers high specificity and sensitivity in detecting CD14, making it a valuable tool for immunology studies, infectious disease research, and inflammation-related investigations. With its reliable performance and compatibility with multiple experimental techniques, the Mouse CD14 Monoclonal Antibody (AF647 Conjugated) SA14-2 (AGEL1871) is an indispensable asset for scientists seeking to advance their understanding of the immune system and related diseases.
Product Title:
GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1871
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.