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GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1879)

SKU:
AGEL1879
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€219 - €549
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (AF488 Conjugated, clone SA14-2) is a specialized tool for researchers investigating the CD14 antigen in mouse samples. This antibody, conjugated with AF488 for enhanced fluorescence detection, specifically targets the CD14 protein found on the surface of immune cells. With its high specificity and sensitivity, this antibody is ideal for a range of applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD14 is a crucial receptor involved in the recognition of bacterial lipopolysaccharides, triggering innate immune responses. By targeting CD14, researchers can delve into the mechanisms of immune activation and inflammation, making this antibody a valuable asset for studies in infectious diseases, inflammatory disorders, and immunology research.

The AF488 conjugation allows for easy visualization and quantification of CD14 expression in various mouse cell types, facilitating detailed analysis and interpretation of experimental results.With its high-quality performance and reliability, the Mouse CD14 Monoclonal Antibody (AF488 Conjugated, clone SA14-2) from Assay Genie offers researchers a robust tool for unraveling the complexities of immune responses in mouse models, paving the way for new insights into immune regulation and potential therapeutic targets.

Product Title:GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1879
Size:25µg, 100µg
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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