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PE/Cyanine7 Anti-Mouse CD122 Antibody [5H4] (AGEL0795)

SKU:
AGEL0795
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€149 - €379
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD122 Antibody [5H4]

The Mouse CD122 Monoclonal Antibody (PE-Cyanine7 Conjugated) 5H4 (AGEL0795) from Assay Genie is a cutting-edge research tool designed for scientists investigating the CD122 protein in mice. CD122, also known as the interleukin-2 receptor beta subunit, plays a crucial role in immune responses and T cell activation.This monoclonal antibody offers high specificity and sensitivity in detecting CD122 in mouse samples, making it an invaluable tool for immunology researchers studying T cell function and immune system regulation. The PE-Cyanine7 conjugation provides fluorescent labeling for easy visualization and analysis by flow cytometry and other fluorescence-based assays.

With its exceptional performance and reliability, the Mouse CD122 Monoclonal Antibody 5H4 (AGEL0795) empowers scientists to delve deeper into the mechanisms underlying immune response modulation and potential therapeutic interventions in conditions such as autoimmune diseases, infectious diseases, and cancer. Accelerate your research and unlock new insights into immune system regulation with this state-of-the-art antibody from Assay Genie.

Product Title:PE/Cyanine7 Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL0795
Size:50 Tests, 100 Tests, 200 Tests
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16297
Gene ID:16185
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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