The Mouse CD11c Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (clone N418) is a powerful tool for researchers studying immune cells expressing the CD11c marker. This antibody, conjugated with PerCP-Cyanine5.5, provides a fluorescent signal that is ideal for flow cytometry applications, allowing for the identification and analysis of CD11c-expressing cells.CD11c is a well-known marker for dendritic cells, a crucial component of the immune system responsible for initiating and regulating immune responses. By targeting CD11c, researchers can effectively study dendritic cell populations in various tissues and conditions. The specificity and sensitivity of the N418 clone ensure accurate and reliable detection of CD11c, enabling detailed investigations into the role of dendritic cells in immunity, inflammation, and disease.
Whether investigating immune responses, inflammatory processes, or immune cell populations, the Mouse CD11c Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (clone N418) offers a valuable tool for researchers seeking to deepen their understanding of the immune system's complexities. Compatible with flow cytometry techniques, this antibody facilitates precise and informative analysis of CD11c-positive cells, making it an essential component of immunological research endeavors.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL0511
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.