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APC Anti-Mouse CD11c Antibody [N418] (AGEL0515)

SKU:
AGEL0515
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
APC
€109 - €269
Frequently bought together:

Description

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APC Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody, APC Conjugated (N418) is a powerful tool for researching immune cells within the body's defense system. This antibody specifically targets the CD11c protein, which is a marker for dendritic cells, a crucial component of the immune system responsible for presenting antigens to T cells. By binding to CD11c, this antibody allows for the visualization and analysis of dendritic cells in various tissues and experimental models. Dendritic cells are essential in initiating and regulating immune responses, playing key roles in both protective immunity and tolerance. By targeting CD11c with this antibody, researchers can explore the functions and interactions of dendritic cells in different contexts, including infection, inflammation, and autoimmune diseases.

The APC conjugation enhances the detection capabilities of the antibody, making it a valuable tool for flow cytometry and other immunological techniques.Overall, the Mouse CD11c Monoclonal Antibody, APC Conjugated (N418), provides a precise and efficient means of studying dendritic cells and their involvement in immune processes. Its specificity and versatility make it an excellent choice for investigations into immunology, vaccine development, and understanding the complexities of the body's defense mechanisms.

Product Title:APC Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0515
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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