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APC Anti-Mouse CD11c Antibody [N418] (AGEL0030)

SKU:
AGEL0030
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
N418
Conjugation:
APC
Applications:
FC
$131 - $299
Frequently bought together:

Description

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APC Anti-Mouse CD11c Antibody [N418]

The APC-Conjugated Mouse CD11c Monoclonal Antibody (N418) is meticulously designed for advanced research targeting CD11c, a crucial cell surface molecule predominantly expressed on dendritic cells and other immune cells involved in antigen presentation and immune response activation. This monoclonal antibody, produced in mice, is highly specific to mouse CD11c and is validated for use in flow cytometry applications. Conjugation with allophycocyanin (APC) ensures bright and stable red fluorescence, enabling precise and reliable detection.CD11c, an integral component of the integrin complex, plays a central role in the immune system by facilitating the capture and presentation of antigens to T cells, thereby initiating and regulating immune responses. Its significance in immune regulation makes it a valuable target for research into autoimmune disorders, infectious diseases, and cancer.

The APC-Conjugated Mouse CD11c Monoclonal Antibody (N418) is an indispensable tool for researchers aiming to investigate dendritic cell function and develop therapies that modulate immune activity.By providing accurate and sensitive detection of CD11c, this antibody supports comprehensive studies of immune response pathways, contributing to the advancement of therapeutic strategies for autoimmune diseases, chronic inflammatory conditions, and immune-related disorders. Understanding the activity of CD11c is essential for developing innovative immunotherapies that leverage or modulate antigen presentation in various disease contexts. This antibody is a critical asset for advancing research in immunology and cancer.

Product Title:APC Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0030
Size:50 Tests, 100 Tests, 200 Tests
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:APC Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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