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GenieFluor 647 Anti-Mouse CD11c Antibody [N418] (AGEL0512)

SKU:
AGEL0512
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
AF 647
€139 - €289
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody (AF647-conjugated) - clone N418 (AGEL0512) offered by Assay Genie is a cutting-edge tool for researchers investigating immune cells expressing CD11c, a key marker for dendritic cells in mice. This monoclonal antibody, conjugated with AF647 for high sensitivity fluorescence applications, is derived from clone N418 and is engineered for superior specificity and performance in flow cytometry and immunofluorescence assays.Dendritic cells are crucial players in the immune system, functioning as antigen-presenting cells that initiate and regulate immune responses. The CD11c molecule is prominently expressed on dendritic cells, making it a reliable marker for identifying and characterizing these specialized immune cells.

By targeting CD11c with the N418 monoclonal antibody, researchers can accurately detect and study dendritic cell populations in complex biological samples, providing insights into immune responses, inflammation, and pathogen recognition dynamics.With its exceptional binding affinity and fluorescent conjugation, the Mouse CD11c Monoclonal Antibody (AF647-conjugated) - clone N418 (AGEL0512) from Assay Genie offers a powerful tool for investigating dendritic cells and their role in various immune processes. This antibody is a valuable resource for studies in immunology, vaccine development, and autoimmune disease research, contributing to advancements in our understanding of immune cell function and potential therapeutic strategies.

Product Title:GenieFluor 647 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0512
Size:50 Tests, 100 Tests, 200 Tests
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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