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PE/Cyanine7 Anti-Mouse CD11a Antibody [FD441.8] (AGEL0835)

SKU:
AGEL0835
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€199 - €409
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody PE-Cyanine7 Conjugated (FD441.8) is a specialized research tool offered by Assay Genie for investigating CD11a, a critical cell surface antigen involved in immune responses, particularly in cell adhesion and migration processes. This antibody is specifically engineered for use in flow cytometry and immunofluorescence applications, making it an essential tool for studies focused on immune cell interactions and inflammatory responses.CD11a, also known as integrin alpha L, is a key component of the Lymphocyte Function-Associated Antigen 1 (LFA-1) complex, which plays a crucial role in mediating cellular interactions within the immune system. By targeting CD11a with this monoclonal antibody, researchers can effectively identify and study various immune cell populations, including T cells, B cells, and natural killer cells, in both healthy and disease states.

With its PE-Cyanine7 conjugation, this antibody offers enhanced sensitivity and signal detection, allowing for accurate and reliable analysis of CD11a expression levels on different cell types. Researchers investigating immune-mediated diseases, such as autoimmune disorders, inflammation, and infectious diseases, can benefit from the precise targeting and detection capabilities of this antibody to further their understanding of immune cell function and pathology.Overall, the Mouse CD11a Monoclonal Antibody PE-Cyanine7 Conjugated (FD441.8) from Assay Genie provides a valuable tool for immunologists and cell biologists alike, enabling detailed examination of CD11a expression patterns and dynamics in diverse experimental settings.

Product Title:PE/Cyanine7 Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0835
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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