The Mouse CD11a Monoclonal Antibody PE/Cyanine5 Conjugated (FD441.8) (AGEL0826) offered by AssayGenie is a cutting-edge tool for research involving CD11a, a key cell surface integrin involved in immune cell adhesion and signaling. This monoclonal antibody, generated against mouse samples, is highly specific and sensitive in detecting CD11a expression in various immune cell populations.CD11a, also known as Lymphocyte Function-Associated Antigen 1 (LFA-1), plays a crucial role in mediating cell-cell interactions, such as T cell activation and migration to sites of inflammation.
The conjugation of PE and Cyanine5 to this antibody allows for multi-color flow cytometry analysis, enabling researchers to study immune cell dynamics and responses in intricate detail.By targeting CD11a, researchers can gain insights into immune cell behavior in health and disease states, making this antibody essential for studies in immunology, inflammation, and infectious diseases. Its reliable performance and versatility in flow cytometry make it a valuable tool for investigating the role of CD11a in immune responses and developing targeted immunotherapies.
Product Title:
PE/Cyanine5 Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0826
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).