The Mouse CD11a Monoclonal Antibody (PE-Cyanine5.5 Conjugated) is a vital tool for researchers studying immunology, particularly in the context of immune cell interactions and functions. This antibody, designated as FD441.8 (AGEL0828), is specifically designed for the detection and analysis of CD11a, also known as integrin alpha L, a key cell surface molecule involved in immune responses.CD11a plays a crucial role in cell adhesion and migration, particularly in the activation and regulation of T cells, mediating their interactions with other immune cells and tissues. By targeting CD11a, researchers can gain insights into processes such as inflammation, immune surveillance, and immune cell-mediated cytotoxicity.The Mouse CD11a Monoclonal Antibody is conjugated with PE-Cyanine5.
5, facilitating its use in flow cytometry and immunofluorescence applications for precise and quantitative detection of CD11a-expressing cells. Its specificity and sensitivity make it an essential tool for investigating immune cell dynamics, immune response modulation, and potential therapeutic targets in various diseases, including autoimmune disorders, infectious diseases, and cancer.For researchers seeking to explore the intricate mechanisms of immune cell function and regulation, the Mouse CD11a Monoclonal Antibody (PE-Cyanine5.5 Conjugated) offers a reliable and versatile solution for in-depth studies and discoveries in immunology research.
Product Title:
PE/Cyanine5.5 Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0828
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).