The Mouse CD11a Monoclonal Antibody (PE Conjugated, FD441), available as FD441-8-AGEL0831 from AssayGenie, is a powerful tool for researchers studying cell adhesion and immune response mechanisms. This antibody specifically targets CD11a, a cell surface glycoprotein crucial for lymphocyte function and interactions with other immune cells.CD11a, also known as Lymphocyte Function-Associated Antigen 1 (LFA-1), plays a vital role in immune response regulation, particularly in leukocyte adhesion and migration. By binding to CD11a, this monoclonal antibody enables the precise detection and visualization of CD11a expression in mouse samples, making it ideal for flow cytometry and other immunological assays.
With its PE conjugation, this antibody offers enhanced signal intensity and multiplexing capabilities, allowing for detailed analysis of CD11a expression levels in different cell populations. Researchers interested in understanding immune cell activation, inflammation, and immune cell trafficking will find this antibody invaluable for their studies.By utilizing the Mouse CD11a Monoclonal Antibody (PE Conjugated, FD441), researchers can gain valuable insights into the role of CD11a in immune responses, autoimmune diseases, and inflammatory conditions. This antibody is a valuable tool for advancing scientific understanding in immunology and related fields.
Product Title:
PE Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0831
Size:
25µg, 100µg
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).