The Mouse CD11a Monoclonal Antibody (APC Conjugated) FD441.8 (AGEL0156) is a powerful tool for researchers studying immune responses and cell adhesion processes. This antibody, generated specifically for mouse samples, is designed to target CD11a, a key integrin receptor involved in immune cell adhesion and migration.CD11a, also known as lymphocyte function-associated antigen 1 (LFA-1), plays a crucial role in mediating the interactions between immune cells and other cell types, contributing to immune surveillance, inflammation, and immune response activation. By targeting CD11a, this monoclonal antibody allows for precise detection and analysis of CD11a expression in various cell populations, facilitating detailed investigations into immune cell behavior and function.The APC conjugation of this antibody enables efficient detection of CD11a in flow cytometry applications, providing valuable insights into the expression levels and distribution of this integrin receptor on different cell populations.
With its high specificity and sensitivity, this antibody is a valuable tool for studies focused on understanding immune cell behavior, cell adhesion processes, and immune system regulation in both normal and disease states.Researchers in immunology, cell biology, and related fields can benefit from the use of the Mouse CD11a Monoclonal Antibody (APC Conjugated) FD441.8 (AGEL0156) to advance their understanding of immune cell interactions, inflammatory processes, and immune responses, ultimately contributing to the development of novel therapeutics for immune-related disorders and diseases.
Product Title:
APC Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0156
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).