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PE Anti-Mouse CD119 Antibody [GR-20] (AGEL1437)

SKU:
AGEL1437
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$323 - $755
Frequently bought together:

Description

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PE Anti-Mouse CD119 Antibody [GR-20]

The Mouse CD119 Monoclonal Antibody (PE Conjugated) - GR-20 (AGEL1437) offered by AssayGenie is a powerful tool for research in immunology and cell biology. This antibody specifically targets CD119, also known as the granulocyte colony-stimulating factor (G-CSF) receptor. The monoclonal antibody is conjugated with PE (phycoerythrin), a bright and stable fluorescent dye commonly used in flow cytometry for cell surface marker analysis. This feature allows for easy and efficient detection of CD119 expression on cell surfaces, facilitating precise identification and characterization of cells expressing this important receptor.

CD119, a key player in hematopoiesis and immune response regulation, is involved in the proliferation and differentiation of neutrophils. Its dysregulation has been linked to various hematological disorders and inflammatory conditions, making it a compelling target for research studies. By utilizing the Mouse CD119 Monoclonal Antibody (PE Conjugated) - GR-20 (AGEL1437), researchers can delve deeper into the functions and mechanisms of CD119, advancing our understanding of immune system dynamics and potential therapeutic interventions.

Product Title:PE Anti-Mouse CD119 Antibody [GR-20]
SKU:AGEL1437
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GR-20
Synonyms:Interferon gamma receptor 1;Ifngr1;IFN-gamma-R1;IFN-gamma-R-alpha;CD119;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15261
Gene ID:15979
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

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