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FITC Anti-Mouse CD117 Antibody [2B8] (AGEL1182)

SKU:
AGEL1182
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
€149 - €359
Frequently bought together:

Description

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FITC Anti-Mouse CD117 Antibody [2B8]

The Mouse CD117 Monoclonal Antibody (FITC-conjugated, 2B8) is a valuable tool for researchers studying CD117, a cell surface receptor involved in various physiological processes, including hematopoiesis and stem cell maintenance. This monoclonal antibody, produced using advanced technology, specifically targets CD117 molecules and is conjugated with FITC for enhanced detection in flow cytometry and immunofluorescence applications.CD117, also known as c-kit or stem cell factor receptor, is a key marker for identifying and isolating hematopoietic stem cells, progenitor cells, and certain cancer stem cells.

Its role in cell proliferation, differentiation, and survival highlights its significance in hematopoiesis and cancer biology research. By utilizing the Mouse CD117 Monoclonal Antibody (FITC-conjugated, 2B8), researchers can effectively study the expression and function of CD117 in various cell types and experimental models, advancing our understanding of stem cell biology and cancer development.

Product Title:FITC Anti-Mouse CD117 Antibody [2B8]
SKU:AGEL1182
Size:50 Tests, 100 Tests, 200 Tests
Clone No:2B8
Synonyms:Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05532
Gene ID:16590
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

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