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Mouse Apoptosis Signaling Pathway Array (17 targets) (SARB0074)

SKU:
SARB0074
Product Type:
Protein Array
Analytes:
AKT (P-Ser473)
ATM (P-Ser1981)
BAD (P-Ser112)
Caspase-3 (P-Asp175)
Caspase-7 (P-Asp198)
CHK1 (P-Ser296)
eIF-2a (P-Ser52)
ERK1/2 (P-Thr202)
P63085
HSP27 (P-Ser82)
IKBa (P-Ser32)
JNK (P-Thr183)
NF-kB P65 (P-Ser536)
p27 (P-Thr198)
p38 (P-Thr180/Tyr182)
P53 (P-Ser15)
SMAD2 (P-Ser245)
TAK1 (P-Ser412)
Reactivity:
Mouse
Applications:
Multiplex Array
$719 - $1,415
Frequently bought together:

Description

system_update_altDatasheet

Mouse Apoptosis Signaling Pathway Array (17 targets) (SARB0074)

The Mouse Apoptosis Signaling Pathway Array (SARB0074) is a powerful tool for studying apoptosis-related proteins in mouse samples. This array includes 17 key targets involved in the apoptosis signaling pathway, allowing researchers to simultaneously detect and analyze multiple proteins in a single experiment.The array is designed for use in various research applications, including drug discovery, biomarker identification, and pathway analysis. Each target is carefully selected to provide comprehensive coverage of the apoptosis signaling pathway, offering valuable insights into the mechanisms of cell death and survival.

With its high sensitivity and specificity, the Mouse Apoptosis Signaling Pathway Array (SARB0074) delivers accurate and reliable results, making it an essential resource for researchers studying apoptosis and its role in disease development and progression. By using this array, researchers can gain a better understanding of the complex processes underlying apoptosis and identify potential therapeutic targets for treating a variety of diseases, including cancer and neurodegenerative disorders.

Product Sku:SARB0074
Size:2, 4, or 8
Species Detected:Mouse
Number of Targets Detected:17
Gene Symbols:AKT1, ATM, BAD, CASP3, CASP7, CDKN1B, CHEK1, EIF2S1, HSPB1, MAP3K7|MAPK14, MAPK8, NFKBIA, RELA, SMAD2, TP53
Compatible Sample Types:Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Lysates
Design Principle:Sandwich-based
Method of Detection:Chemiluminescence
Pathway:Akt Signaling / HER/ErbB Signaling / HIF-1 alpha Signaling / IGF Signaling / JAK/STAT Signaling / MAPK Signaling / mTOR Signaling / NFkB Signaling / p53 Signaling / PI3K-AKT Signaling / PKC Signaling / TGF-beta Signaling
Quantitative/Semi-Quantitative:Semi-Quantitative
Solid Support:Membrane
Suggested Application(s):Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process
Storage/Stability:For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period.
Once thawed, store array membranes at -20°C and all other reagents undiluted at 4°C for no more than 3 months.
Hover over target for more information
AKT (P-Ser473)
  • Gene Symbol: Akt1 Akt Rac
  • Gene ID: 11651
  • Accession #: P31750
ATM (P-Ser1981)
  • Gene Symbol: Atm
  • Gene ID: 11920
  • Accession #: Q62388
BAD (P-Ser112)
  • Gene Symbol: Bad Bbc6
  • Gene ID: 12015
  • Accession #: Q61337
Caspase-3 (P-Asp175)
  • Gene Symbol: Casp3 Cpp32
  • Gene ID: 12367
  • Accession #: P70677
Caspase-7 (P-Asp198)
  • Gene Symbol: Casp7 Lice2 Mch3
  • Gene ID: 12369
  • Accession #: P97864
CHK1 (P-Ser296)
  • Gene Symbol: Chek1 Chk1
  • Gene ID: 12649
  • Accession #: O35280
eIF-2a (P-Ser52)
  • Gene Symbol: Eif2s1 Eif2a
  • Gene ID: 13665
  • Accession #: Q6ZWX6
ERK1/2 (P-Thr202)
  • Gene Symbol: N/A
  • Gene ID: N/A
  • Accession #: Q63844 | P63085
HSP27 (P-Ser82)
  • Gene Symbol: Hspb1 Hsp25 Hsp27
  • Gene ID: 15507
  • Accession #: P14602
IKBa (P-Ser32)
  • Gene Symbol: Nfkbia Ikba
  • Gene ID: 18035
  • Accession #: Q9Z1E3
JNK (P-Thr183)
  • Gene Symbol: Mapk8 Jnk1 Prkm8
  • Gene ID: 26419
  • Accession #: Q91Y86
NF-kB P65 (P-Ser536)
  • Gene Symbol: Rela Nfkb3
  • Gene ID: 19697
  • Accession #: Q04207
p27 (P-Thr198)
  • Gene Symbol: Cdkn1b
  • Gene ID: 12576
  • Accession #: P46414
p38 (P-Thr180/Tyr182)
  • Gene Symbol: Mapk14 Crk1 Csbp1 Csbp2
  • Gene ID: 26416
  • Accession #: P47811
P53 (P-Ser15)
  • Gene Symbol: Tp53 P53 Trp53
  • Gene ID: 22059
  • Accession #: P02340
SMAD2 (P-Ser245)
  • Gene Symbol: Smad2 Madh2 Madr2
  • Gene ID: 17126
  • Accession #: Q62432
TAK1 (P-Ser412)
  • Gene Symbol: Map3k7 Tak1
  • Gene ID: 26409;
  • Accession #: Q62073
  • Easy to use
  • No specialized equipment needed
  • Compatible with nearly any liquid sample
  • Proven technology
  • Highly sensitive (pg/ml)
  • Sandwich ELISA specificity
  • Higher density than ELISA, Western blot or bead-based multiplex
  • Mouse Apoptosis Signaling Pathway Antibody Array C1 Membranes
  • Blocking Buffer
  • Detection Antibody Cocktail
  • 1,000X HRP-Anti-Rabbit IgG Concentrate
  • 20X Wash Buffer I Concentrate
  • 20X Wash Buffer II Concentrate
  • 2X Cell Lysis Buffer Concentrate
  • Detection Buffer C
  • Detection Buffer D
  • 8-Well Incubation Tray w/ Lid
  • Protease Inhibitor Cocktail
  • 100x Phosphatase Inhibitor Cocktail I
  • Phosphatase Inhibitor Cocktail II
  • Plastic Sheets
  • Array Map Template

Other Materials Required

  • Pipettors, pipet tips and other common lab consumables
  • Orbital shaker or oscillating rocker
  • Tissue Paper, blotting paper or chromatography paper
  • Adhesive tape or Saran Wrap
  • Distilled or de-ionized water
  • A chemiluminescent blot documentation system , X-ray Film and a suitable film processor, or another chemiluminescent detection system.
1.Block membranes
2.Incubate with Sample
3.Incubate with Detection Antibody Cocktail
4.Incubate with HRP-Conjugated anti-IgG
5.Incubate with Detection Buffers
6.Image with chemiluminescent imaging system
7.Perform densitometry and analysis

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