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Mouse alpha/beta TCR monoclonal antibody (PE) (AGIM0542)

SKU:
AGIM0542
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
H57-597
Conjugation:
PE
Applications:
FC
$215
Frequently bought together:

Description

system_update_altDatasheet
Product Name:Mouse alpha/beta TCR monoclonal antibody (PE)
Product Code:AGIM0542
Size:100 µL
Reactivity:Mouse
Clone:H57-597
Applications:Flow Cytometry
Conjugate:PE
Isotype:IgG
Host Species:Hamster
Storage:Store at 4°C. Avoid prolonged exposure to light.
Uniprot:P0C6B2
Background:The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCRCD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

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