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Mouse ABL1/c-Abl Recombinant Protein (His tag)

SKU:
RPES5782
Product Type:
Recombinant Protein
Species:
Mouse
$179
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Description

Product Name:Mouse ABL1/c-Abl Recombinant Protein (His tag)
Product Code:RPES5782
Size:20µg
Species:Mouse
Expression Host:E.coli
Synonyms:Abelson tyrosine protein kinase 1, ABL 1, bcr/abl, JTK7, p150, Proto-oncogene c-Abl, v abl
Mol Mass:21.12 kDa
AP Mol Mass:25 kDa
Tag:N-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met 1-Asn 193
Accession:P00520
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

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