MonoMethyl-Histone H3-R2 Rabbit Monoclonal Antibody (CAB19645)
- SKU:
- CAB19645
- Product Type:
- Antibody
- Applications:
- WB
- IP
- ChIP
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | MonoMethyl-Histone H3-R2 Rabbit Monoclonal Antibody |
SKU: | CAB19645 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic monomethylated peptide around R2 of human Histone H3 (Q16695). |
Sequence: | MART KQTA RKST GGKA PRKQ LATK AARK SAPA TGGV KKPH RYRP GTVA LREI RRYQ KSTE LLIR KLPF QRLV REIA QDFK TDLR FQSS AVMA LQEA CEAY |
Tested Applications: | WB ELISA DB CUT&Tag |
Recommended Dilution: | DB,1:500 - 1:1000 WB,1:500 - 1:1000 CUT&Tag, 10⁵ cells /1 μg |
Synonyms: | H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A; MonoMethyl-Histone H3-R2 |
Positive Sample: | HeLa nuclear extract, C6 nuclear extract |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, nucleus |
Calculated MW: | 16kDa |
Observed MW: | 17kDa |
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8290/8350 |
Clone Number: | ARC0124 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |