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Mono-methyl-HIST1H2BC (K23) Antibody (PACO65045)

SKU:
PACO65045
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

Mono-methyl-HIST1H2BC (K23) Antibody (PACO65045)

The Mono-Methyl Hist1H2BC (K23) Antibody (PAC065045) is a key tool for researchers studying histone modifications and epigenetic regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various assays, including Western blotting and immunofluorescence.Histone modifications, such as mono-methylation of histone H2B at lysine 23, play a crucial role in gene regulation and chromatin structure. The Mono-Methyl Hist1H2BC (K23) Antibody allows for the detection and analysis of this specific histone modification, providing valuable insights into epigenetic mechanisms and their impact on gene expression.

Researchers in the fields of molecular biology, genetics, and cancer biology will find this antibody essential for investigating the role of histone modifications in various biological processes and disease states. By targeting the mono-methyl histone H2B at lysine 23, this antibody opens up new possibilities for understanding epigenetic regulation and developing targeted therapies for diseases influenced by histone modifications.

Product Name:Mono-methyl-HIST1H2BC (K23) Antibody
Product Code:PACO65045
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17-28aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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