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Mono-methyl-HIST1H2BC (K15) Antibody (PACO65131)

SKU:
PACO65131
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

Mono-methyl-HIST1H2BC (K15) Antibody (PACO65131)

The Mono-Methyl Hist1H2bc (K15) Polyclonal Antibody (PAC065131) is a valuable tool for researchers studying histone modifications and their impact on gene expression and chromatin structure. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting the mono-methylation of histone H2bc at lysine 15 in human samples. Validated for use in various applications including Western blot and immunofluorescence, this antibody allows for precise detection and analysis of the histone modification in different cell types.Histone modifications play a crucial role in the regulation of gene expression and chromatin remodeling, impacting various cellular processes such as cell differentiation, development, and disease progression.

The mono-methylation of histone H2bc at lysine 15 is a specific modification associated with gene regulation and can provide insights into the epigenetic mechanisms underlying various diseases, including cancer and neurological disorders.By studying the role of mono-methyl histone H2bc (K15) in gene expression and chromatin dynamics, researchers can gain a better understanding of how epigenetic changes contribute to disease development and progression. This antibody serves as a valuable tool for investigating the functional significance of histone modifications and their implications in a wide range of biological processes.

Product Name:Mono-methyl-HIST1H2BC (K15) Antibody
Product Code:PACO65131
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (9-20aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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