The MON1A Polyclonal Antibody (CAB17946) is a valuable tool for researchers studying the MON1A protein, a key regulator of endosomal trafficking. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MON1A protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in cell biology and molecular biology.MON1A plays a crucial role in the endosomal pathway, regulating the transport of proteins and lipids within cells. Dysregulation of MON1A function has been implicated in various diseases, including neurodegenerative disorders and lysosomal storage diseases.
As such, understanding the mechanisms of MON1A activity is essential for developing targeted therapies for these conditions.By utilizing the MON1A Polyclonal Antibody (CAB17946), researchers can gain valuable insights into the function of the MON1A protein and its role in cellular processes. This antibody provides a reliable tool for investigating the molecular mechanisms underlying endosomal trafficking, ultimately advancing our knowledge of cell biology and offering potential avenues for therapeutic interventions.
Product Name:
MON1A Rabbit Polyclonal Antibody
SKU:
CAB17946
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant protein of human MON1A.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
SAND1; MON1A
Positive Sample:
K-562
Cellular Localization:
cytosol, Mon1-Ccz1 complex
Calculated MW:
73kDa
Observed MW:
73kDa
Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within cellular iron ion homeostasis and protein transport. Part of Mon1-Ccz1 complex.
Purification Method:
Affinity purification
Gene ID:
84315
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of K-562 cells, using MON1A antibody (CAB17946) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2min.
